Seborrheic dermatitis, tinea versicolor and Malassezia Folliculitis is a common skin disease in Department of Dermatology, but many people d
Seborrheic dermatitis, tinea versicolor and Malassezia Folliculitis is a common skin disease in Department of Dermatology, but many people do not know that they are actually caused by the culprit of a spherical fungus - small malassezia!
Malassezia is a kind of yeast like fungus, which is resident on the surface of human skin. Because of Malassezia rich lipase, can be decomposed into lipid fatty acids, thereby providing nutrition required for their metabolism, so the Malassezia love parasites on the body sebaceous gland rich parts such as the head, facial canal and chest, back skin. Popular said, where the oil and water, it likes to multiply where. At the same time, it is also an opportunistic pathogen, that is to say, does not cause any disease under normal circumstances, in certain circumstances, when the balance is broken, such as a variety of factors caused by the sebaceous glands, the skin surface microflora imbalance, Malassezia overgrowth can cause illness. Here we come to know that it often caused by several common skin diseases.
1 seborrheic dermatitis (seborrheic dermatitis)
Seborrheic dermatitis is a place in the head and face, chest and back, seborrhea more parts of a chronic inflammatory skin disease. The rash appears as oily skin based on mild erythema, covered with greyish white bran like scales, with mild pruritus, rash with extended, visible greasy yellow scales, map like patches; serious exudation, with a thick crust, which occurred in the head can also cause seborrheic dermatitis, seborrheic alopecia.
The latest study found that there is a close relationship between colonization and infection and the pathogenesis of equine seborrheic dermatitis of Malassezia. The pathogenesis may be: on the basis of the genetic basis of the overflow of the body, the bacteria in the hydrolysis of triglycerides in sebum, the production of free fatty acids further stimulate skin inflammation.
Popular to say that, seborrheic dermatitis and skin oily physique, but oily skin fitness will be very oil, does not necessarily appear seborrheic dermatitis, only when these lipophilic Malassezia, will cause inflammation appear parasitic seborrheic dermatitis after infection. In addition, spirit, diet, lack of vitamin B group, alcohol and other factors can also affect the occurrence and development of seborrheic dermatitis.
2 Malassezia Folliculitis (Malassezia folliculitis)
Malassezia Folliculitis or pityrosporum folliculitis, more common in middle-aged men, skin lesions and hair follicle, hemispherical red papules, diameter 2-4mm, often have oily gloss, around flush, mainly in the chest and the back, neck, shoulder, upper arm, waist and abdomen, diffuse scattered rash up to tens to hundreds, densely arranged, but not fused, consciously or with mild itching, burning and tingling, and a small number of cases may exist with tinea versicolor.
Malassezia Folliculitis is the pathogenesis of Malassezia blooms in the hair follicle caused. Malassezia lipase will hair follicle glycerol three vinegar is decomposed into free fatty acids, stimulates the hair follicles mouth produce scaling, and blocked pores, sebum retention. The stimulation of free fatty acids led to the release of hair follicle contents into the surrounding tissues, resulting in inflammation.
Tinea versicolor (tinea versicolor) 3
Because of local lesions of pityriasis versicolor, hyperpigmentation or hypopigmentation name. Because the skin lesions often in hot summer rash located in multiple sweat gland rich parts of, it is commonly known as sweat stain. In fact it is Malassezia invasion of skin superficial fungal infection caused by chronic cuticle, lesion morphology for raindrop, nummular or confluent, covered with a small number of fine bran like scales, sometimes lesions in various colors such as brown, gray and white, pale red, this is because the Malassezia can produce dihydroxy acid inhibition and cytotoxic effects on melanocytes, disturbance of local skin melanin particles synthesized by.
The same occurs in the trunk of pityriasis versicolor sebaceous gland rich parts such as chest, back, arm, abdomen, axillary, usually mild symptoms, onset is slow, occurs in adult males.
In conclusion, although seborrheic dermatitis, tinea versicolor and Malassezia Folliculitis clinical manifestations vary, but are caused by Malassezia infection, so the treatment should be the first choice for the treatment of anti fungal treatment. Mild topical antifungal lotion, ointment and other treatment can be more serious, recurrent and can be treated with oral antifungal drugs, combined with appropriate symptomatic treatment, can achieve satisfactory results.
Author: Dr. Dong Qingsheng Department of Dermatology the Second Affiliated Hospital of Chengdu University of Traditional Chinese Medicine