Liver function test is a variety of biochemical tests to detect the liver function related to the various indicators to reflect the basic si
Liver function test is a variety of biochemical tests to detect the liver function related to the various indicators to reflect the basic situation of liver function. Because of the variety of liver function, there are many methods of liver function examination. The protein and liver function examination of serum total protein, albumin and globulin ratio, serum turbidity and floc and AFP checks; serum enzymes and liver disease associated with alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and lactate dehydrogenase; test related biotransformation and excretion of the bromsulphalein test etc. test; associated with bile pigment metabolism, such as urine and bile of three bilirubin quantitative test, combined with the history and symptoms to select a group of one or several tests, there are helpful to diagnosis and evaluation of liver function.
1, the index of liver parenchyma damage
Alanine aminotransferase (ALT), aspartate aminotransferase (AST), including ALT, which is the most commonly used sensitive indicators, 1% of liver cells necrosis, serum ALT levels can be increased by up to 1 times. AST continues to rise, more than ALT value often prompts the liver damage is serious, is a sign of increasing chronicity.
2, the index of bilirubin metabolism and cholestasis
The main contents include total bilirubin (TBil), direct and indirect bilirubin, Urine Bilirubin, urine, bile acid (TBA), gamma glutamyl aminopeptidase (gamma GT) and alkaline phosphatase (ALP), etc.. Hepatocyte degeneration, necrosis, bilirubin metabolism disorder or intrahepatic cholestasis, these indicators can be increased. Hemolytic jaundice, indirect bilirubin can rise.
3, the index of liver function
Including albumin, prealbumin, cholinesterase and prothrombin time and activity, long-term decreased albumin and cholinesterase, prothrombin activity decreased, vitamin K can not correct, normal liver cells decreased gradually, hepatocyte protein synthesis, coagulation function, liver dysfunction, poor prognosis.
4, the index of liver fibrosis
It mainly includes type III procollagen (P III P), type IV collagen (C - IV), hyaluronic acid (HA), and LN, which may be helpful in the diagnosis of liver fibrosis and early cirrhosis.
Liver function examination notice
Liver function test, must be fasting blood test. Fasting time is generally 8~12 hours, for the initial examination of liver function, especially should be so. The best day before the withdrawal of alcohol. There was a certain relationship between the content of liver function test and diet. Such as drinking, easy to make some of the serum enzyme value, eat greasy food can increase blood lipids.
General is the morning of the test, so the day after getting up on an empty stomach, water can not drink.