Painless treatment of early skin cancer, photodynamic therapy

Basal cell carcinoma and squamous cell carcinoma is the most common clinical two skin cancer, the main method for the treatment of the past

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Basal cell carcinoma and squamous cell carcinoma is the most common clinical two skin cancer, the main method for the treatment of the past is surgery, cryotherapy and laser medicine, etc., often the effect is not ideal, but also easy to cause pain, dermatitis, disfigurement, deterioration and other adverse consequences for patients with more pain.

In fact, photodynamic therapy should be the first choice for the treatment of early stage squamous cell carcinoma (SCC) and squamous cell carcinoma (1.5cm) with a superficial phenotype or an entity of less than 2 cm in diameter. The principle is that malignant tumor cells can selectively absorb exogenous photosensitizer into protoporphyrin in cells, the red light of specific wavelength after photodynamic reaction, the generation of reactive oxygen and kill the tumor cells and the surrounding normal tissue cells were not affected by any.

The current clinical treatment in the dark environment, with aminolevulinic acid solution of 10% wet compress in the lesion or tumor surface, covering the area beyond the edge of the lesions around 1cm, packet film after 3 hours with 395nm UV light detection of porphyrin, see the brick red fluorescence can continue to receive photodynamic irradiation treatment, according to the size of lesions to adjust the spot. Each day about 30 minutes, the larger lesions, due to large spot, irradiation time prolonged corresponding, or increase the dose of irradiation, irradiation control in 72 ~ 100J/cm2, 1 ~ 2 weeks after the next treatment. Usually after 2 to 6 treatment, the total cure rate of up to 95 ~ 100%, only a small number of people with local pain and other adverse reactions, but can be tolerated.

As a new type of body surface tumor ablation therapy, photodynamic therapy in the treatment of basal cell carcinoma and squamous cell carcinoma has the advantages of less pain, simple operation and good curative effect.

 

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