Treatment of perianal condyloma acuminatum

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The treatment of perianal condyloma acuminatum is a sexually transmitted disease caused by human papilloma virus (HVP), such as genital, per

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The treatment of perianal condyloma acuminatum is a sexually transmitted disease caused by human papilloma virus (HVP), such as genital, perineum and anus. Because of perianal skin and more wrinkles when walking more friction, so in case of condyloma acuminatum often produce perianal condyloma. Perianal condyloma at the beginning for the majority of papules, then showed wart like growth. A large pedunculated cauliflower, see more with small papillary plaque, flat surface. As a result of secondary infection, secretions often have a bad smell. Perianal condyloma acuminatum latency of 3 weeks to 8 months, average 3 months, more common in young and middle-aged men and women are sexually active, the peak age of onset was 20-30 years old, the treatment way is divided into systemic therapy and local treatment with topical therapy directly from the damage of condyloma acuminatum, with therapy as adjuvant therapy, including refrigeration, electric surgery, surgical resection, microwave, laser and photodynamic therapy. The aminolevulinic acid photodynamic therapy (ALA-PTD) is used in the synthesis of hemoglobin ALA through a series of enzymatic reactions to produce protoporphyrin (Pp) principle of photosensitive material, to a large number of exogenous ALA, tumor cells or cells of exuberant growth and selective absorption of ALA in cells transformed into endogenous Pp, the latter in the specific wavelength light irradiation, the cells to produce active peptide oxygen, thereby killing the tumor cells or cells of exuberant growth, but have no effect on normal cells. The specific therapy is first topical ALA solution after dressing, 3 ~ 4 hours, the 632.8nm of He Ne laser irradiation, 1 after 3 weeks of treatment, the time interval of 10 days, the overall clearance rate was 95 ~ 100%, the total recurrence rate was only about 5%. The operation has the characteristics of painless, fast recovery and low recurrence.

 

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