Reasons for the ineffective treatment of asthma drugs (reproduced by the author of the popular medicine: Jin Meiling)

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Living exampleMs. Wang suffering from asthma for more than 2 years. Half a year ago, she was in a hospital department of respiration, the do


Living example

Ms. Wang suffering from asthma for more than 2 years. Half a year ago, she was in a hospital department of respiration, the doctor gave Salmeterol Xinafoate and Fluticasone Propionate Powder for Inhalation (Shu Lidie) in the morning and 1 suction treatment, Ms. Wang did not improve symptoms, but still insist on the use of 3 months, the number and degree of asthma has not been reduced, each attack required intravenous injection of dexamethasone and aminophylline can alleviate.

Recently, Ms. Wang cannot control due to asthma, asthma to outpatients in our hospital, when the doctor found Ms. Wang in pain, depression, due to long-term intravenous injection of dexamethasone, there had been a "full moon face". The doctor let Ms. Wang out of the salmeterol and fluticasone propionate used by her, let her on the spot in accordance with her usual inhalation method of inhalation of a drug. Ms. Wang opened the quasi device, push the slider to a cracking sound, she put the slide bar back in situ, and the nozzle in the mouth and sucking medicine. She is quasi satisfied stuck to a lot of white powder.

Ms. Wang to see the way to absorb the drug, doctors understand why Ms. Wang inhaled corticosteroids combined with bronchodilator drugs are still ineffective treatment of reasons. The original Ms. Wang every time when the drug is to absorb the quasi nano device on the mouth, in fact, she did not inhale the drug in the airway.

There are 4 reasons for the effectiveness of anti asthma drugs

Department of respiration Zhongshan Hospital Affiliated to Fudan University chief physician Jin Meiling

Asthma is a common chronic airway inflammatory disease, which has both chronic airway inflammation and bronchial smooth muscle constriction. Therefore, the long-term use of inhaled corticosteroids and long-acting beta 2 receptor agonists, can make the majority of asthma patients to achieve clinical control of asthma. Unfortunately, we often encounter a lot of patients with poor control of asthma in clinical work, analysis of the reasons, there are 4:

First, did not adhere to long-term medication

Asthma is a chronic disease, and diabetes, high blood pressure, the need for long-term medication. Asthma patients can receive inhaled anti-inflammatory, antispasmodic drugs in the treatment of severe illness, but the symptoms improved significantly or control, some patients without reduction or withdrawal, leading to repeated attacks of asthma, poor control. At present, the Chinese guidelines for the prevention and treatment of asthma: the asthma control, patients still have to maintain the original treatment level for at least 3 months, only to consider reducing. After that, the minimum dose of inhaled corticosteroids should be maintained for more than 1 years, such as asthma remains under control. If too early, too fast to reduce drug withdrawal, is bound to lead to uncontrolled asthma.

Two, the dosage is insufficient

The treatment level of asthma is divided into 5 grades, from low to high, the level of treatment has been strengthened, and the dosage is increasing. If the disease is severe asthma patients, for fear of side effects of drugs, (local treatment does not appear these reactions) and the initial use of lower doses of inhaled corticosteroids, will cause asthma control, lose confidence in treatment. To this end, experts recommend: patients should strictly follow the doctor's advice. Usually, the doctor will be based on the patient's condition, choose the appropriate level, the use of different doses of drugs in order to achieve the purpose of controlling asthma symptoms and reduce adverse drug reactions. Moreover, compared with systemic corticosteroids, the side effects of inhaled corticosteroids have been significantly reduced in patients with the same efficacy, and patients should not worry too much.

Three, inhaled drug method is wrong

Inhalation therapy is the main method of asthma, and whether the inhalation method is correct or not is directly related to whether the drugs play an important role. Ms. Wang introduced in front of the drug is due to the wrong method, so that the drug failed to enter the airway to play a role, leading to asthma can not control. Therefore, asthma patients must correctly grasp the skills of inhaled drugs. At present, there are many kinds of inhalation devices in clinic. The inhalation of different devices is not the same. When the doctor in the prescription of inhaled drugs, most patients will face to face the correct way to teach the patient, the patient can also look at the drug DVD, look at the drug guide pictures, etc., to learn how to breathe. Note that it is difficult to understand the drug instruction alone. Follow up, the patient can also take the initiative to the doctor to demonstrate the method of drug absorption, in order to facilitate the doctor to correct errors in a timely manner.

Four, inhaled drugs feel bad

Some dry powder inhalation of drugs due to the low dose, subtle, no feeling after the pharyngeal cavity, some patients will have an illusion that the drug has no effect, it is not allowed to stop, so that will be out of control of asthma. Think there are patients after inhalation of the oropharynx without feeling, because of drug dose too little, so these patients repeatedly inhaled medications may result in overdose, adverse drug reactions, the waste of medical resources. Some patients think that the quantitative aerosol name they use did not change, but the taste has changed a lot, there is no drug fog after the entrance of the cool feeling. In fact, patients do not have too much attention to changes in aerosol taste, should still be used to regulate the treatment of disease, to maintain good health.

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