Can the sexual precocity of periphery change into central sex precocity?Peripheral precocious into central precocious puberty, that is to sa
Can the sexual precocity of periphery change into central sex precocity?
Peripheral precocious into central precocious puberty, that is to say, precocious puberty can be transformed into true precocious puberty. The mechanism is that peripheral precocious puberty, due to the secretion of sex hormone synthesis and intake of exogenous or endogenous hormones increase, increased levels of sex hormones in the body, can be applied to bone on the one hand, the mature acceleration; on the other hand sex hormones can also direct effect on the central excitation of hypothalamic pituitary gonadal axis activity.
The study found that in recent years, the gonadotropin releasing hormone gene in estrogen responsive memory components of the classic peripheral levels of sex hormones, such as estrogen synthesis, can stimulate the lasting increase of gonadotropin-releasing hormone secretion, and induce precocious puberty. In the clinical onset of these children showed peripheral precocious puberty, but when the sudden increase of bone age, was transformed into central precocious puberty.