Treatment of peripheral arterial disease: treatment strategies for PAD include risk factors, physical exercise, drug therapy, and revascular
Treatment of peripheral arterial disease: treatment strategies for PAD include risk factors, physical exercise, drug therapy, and revascularization. Smoking is the most important risk factor associated with PAD, which can delay the progression of PAD and reduce the risk of myocardial ischemia and other vascular diseases. Less than 10% of patients in their efforts to quit smoking success, but the doctor's advice can improve the success rate of patients with smoking cessation of up to 30%, nicotine replacement products can improve the success rate of long-term smoking cessation. Blood glucose control can reduce the incidence of PAD, relieve the clinical symptoms of intermittent claudication, severe diabetic patients need intensive insulin therapy. Effective control of blood pressure and blood lipids is also necessary, blood pressure and lipid levels and the same degree of coronary heart disease. Beta blockers can worsen claudication in some cases symptoms, need to be used with caution. Physical exercise is an effective method for the treatment of PAD, can significantly improve walking ability, improve blood viscosity, improve blood oxygen carrying capacity, reduce ischemia. Each exercise time of more than 30 minutes to reach the best results, at least 3 times a week, duration of more than 3 months. Antiplatelet therapy can significantly reduce the incidence of cardiovascular and cerebrovascular diseases and the mortality rate in patients with PAD, improve clinical symptoms, reduce the need for surgery, and can improve the patency of blood vessels after transplantation, unless contraindicated, all PAD patients should receive antiplatelet therapy. Antiplatelet drugs including aspirin, chlorine, Bigley cilostazol, cilostazol is a type III phosphodiesterase inhibitor, is the only drug in anti platelet, dilation of blood vessels and anti intimal thickening effect in a body.
Revascularization procedures include vascular bypass surgery and medical intervention. When PAD is too heavy to improve the symptoms of drug therapy, the need for revascularization treatment. Vascular bypass grafting can choose to use artificial blood vessels or autologous blood vessels for transplantation. Extensive disease, complicated aneurysms and atheroemboli are bypass indications. However, bypass grafting is a kind of invasive treatment, with high mortality and complication rate. With the development of interventional cardiology, PAD interventional treatment technology has rapidly improved, endovascular stent implantation is replaced by vascular bypass grafting, and has become the main method for the treatment of PAD. Because of the intervention of PAD and the accumulation of doctors' experience, the success rate and safety of operation were improved obviously, and the complications were significantly reduced. The Department of Cardiology interventional physicians involved in the field of peripheral artery disease, according to the specific situation of patients with one or more interventional treatment, but also make the preoperative diagnosis and treatment, operation and postoperative treatment are very good unity. At present, it is suggested that PAD should be treated early to prevent severe limb ischemia.
Gene therapy is a promising new method for PAD treatment, which can prevent amputation in patients with end-stage PAD. However, because of its long-term efficacy and adverse reactions are not clear, gene therapy is still controversial. Gene therapy can be used to introduce the gene of vascular growth factor into the calf muscle, and to promote the development of new collateral vessels by secreting cytokines.
In a word with the understanding of PAD is greatly improved, through better control of risk factors, and with the new treatment method, the treatment of PAD bottleneck will be broken; interventional therapy and gene therapy technology has become increasingly mature in future will bring new hope to patients with PAD.
Treatment of vasculitis:
1, vascular bypass surgery, we understand that vascular bypass surgery. In fact, with the bypass is a means, but the lesions appear in the body, and the lower extremities, such as the lesions confined to a few centimeters, more than a dozen centimeters, we can discard this section of the road, and then opened a new road. There are two possibilities, one is that it takes a lot of work to repair it, it is better to another one, and the other is that it can not be repaired, then an artificial blood vessel. We need to ensure that the blood supply below knee joint.
2, drug nuclear physical therapy. Drug treatment is mainly to the chest of the vascular disease, or further deterioration of the disease we can inhibit it by drugs.
3, interventional therapy. Interventional therapy is equivalent to an endovascular surgery, surgery is not needed to complete the operation effect. Among the most representative of the interventional techniques is the intravascular ultrasound ablation technology, through the use of a wavelength of ultrasound to plug the blocked blood vessels.
The use of the treatment method is based on the specific circumstances of the patient, involving a number of factors, there are strict definition of medicine. We can understand the simple, for example, is a vascular mountain tunnel, due to various reasons, such as earthquakes or soil erosion, to collapse, or has collapsed, then we have to quickly check, see what happens if the tunnel completely collapsed, that there is no way, call a that is what we say the bypass surgery, if local falling stone, or a little crack, then we put the tunnel cleaning, as mentioned earlier, there is an ultrasound ablation technique. If there is only a little water in the tunnel from the local, with a little cement, mountain trees, keeping about soil and water loss, this is the drug treatment according to the patient's specific situation, in medicine is clinical application according to the stenosis, lesion length, whole body disease state, use the many patients are more interventional therapy, interventional therapy to patients because the blow is very small, and the interventional treatment of repeated operations is very good, the patient can tolerate. Interventional and surgical treatment, we can definitely take them apart, can complement each other.
Reynolds syndrome is often in the cold or emotional disease, showed pale fingers, seizure turned purple, then flush. Should pay attention to prevention, heat preservation, avoid smoking, trauma, clear spiritual concerns; try to avoid exposure to cold, cold, dry contact in daily life drink alcoholic beverages, protection from fingers, stab, cut, to prevent smoking, emotions and other mental factors.
The treatment of vascular diseases mainly according to the different stages of disease progression in addition to vascular surgery and interventional radiology treatment, an important disease and pain is complicated, pain in subjects for vascular disease before doing a lot of research, in addition to continuous nerve block past the sympathetic, at present spinal cord stimulation in foreign applications more and more widely, due to economic conditions, carried out at home is not much, especially for some may need to be amputated and don't want to amputation patients, the related research proves that this treatment can greatly reduce the amputation rate.