2004 IARC (International Cancer Research Center) concluded: HPV (human papilloma virus) infection is a necessary factor for cervical cancer
2004 IARC (International Cancer Research Center) concluded: HPV (human papilloma virus) infection is a necessary factor for cervical cancer and cervical intraepithelial neoplasia occurred; no persistent HPV infection, the possibility of female cervical cancer is almost zero. HPV detection as a means of screening can be concentrated in high-risk populations, so the HPV can be incorporated into the screening program for cervical cancer. 2012 guidelines for cervical cancer screening in the United States have been proposed: cytological and HPV screening programs at the same time.
High risk HPV is a major risk factor for the occurrence and development of cervical cancer, which makes the detection of high-risk HPV as an effective screening technique for cervical cancer. HPV typing detection has been paid more and more attention, and its significance lies in: 1. 2 guide further treatment of patients with ASCUS, LSIL, HSIL. 3 to provide data for the development of HPV vaccine.
In a multicenter study of 3607 patients with cervical cancer in, which was reported by IARC, the average infection rate of type HPV16 in all patients with HPV positive cervical cancer was 57.4%, HPV18. As a result, HPV16 and 18 have a strong predictive function for cervical cancer risk.