Cervical cancer is one of the most common malignant tumors in women, and the incidence rate is second. The total number of new cases of cerv
Cervical cancer is one of the most common malignant tumors in women, and the incidence rate is second. The total number of new cases of cervical cancer accounts for 28.8% of the world. In recent years, there has been a breakthrough in the etiology of cervical cancer. It is necessary to establish the virus (human papiloma, HPV) infection. However, cervical cancer and its precancerous lesions can be cured by early detection. Through regular TCT (Thinprep Cytologic Test, TCT) screening, can accurately sensitively detect early cervical cancer and precancerous lesions, early aggressive treatment lesions, can block the progress of the disease, to prevent cervical cancer especially invasive carcinoma.
TCT examination is the detection of cervical cells and TBS by liquid based thin-layer cell detection system (The Bethesda System, TBS) descriptive diagnostic cytology, it is a kind of cervical cancer cytology technology is currently the most advanced, and the traditional cervical scraping smear examination compared with Papanicolaou staining on the production technology of a major breakthrough, the methods: cell distribution, clear image, improves the detection rate of abnormal cervical cells and specimens of the satisfaction of the relevant data shows that TCT on cervical cancer cell detection rate reaches above 95%, and can detect precancerous lesions; such as fungi, trichomonas, chlamydia and HPV virus infection of microorganism. TCT liquid based cervical cytology sampling convenient, non-invasive, painless, easy to accept; but the cost is not high, to check regularly; using this method to carry out extensive surveys, have important significance to the finding of early cervical cancer.
Cervical cell TBS classification is 1988 by 50 cytopathologists America in Washington, Maryland, Bethesda (Bosaisida) held a meeting to determine, after several times of modification. The TBS report system will cervical squamous intraepithelial lesions were divided into five types: (1) atypical squamous cells of undetermined significance (ASC-US), refers to the slight changes in the occurrence of cervical cells, but not to the extent of low-grade lesions (LSIL), these patients need 3 months TCT cell examination; (2) atypical squamous cells, does not exclude HSIL (ASC-H): refers to the possible precancerous lesions, but it is not exactly heterotype cell diagnosis, these patients should do colposcopy and biopsy to confirm the diagnosis when necessary; (3) low grade squamous intraepithelial lesion (LSIL): a histopathological grade CIN 1 (mild dysplasia), found some suspicious precancerous cells, but not cancer cells, this stage of the condition part will subside, should be 3 months by TCT or vaginal cytology. Endoscopy; (4) the height of intraepithelial lesions (HSIL): the equivalent of histopathological grade CIN2-3 (moderate to severe atypical hyperplasia, carcinoma in situ), suspicious precancerous cells or precancerous cells, without further diagnosis and appropriate treatment for cancer, the development of the larger. Should be promptly taken pathological biopsy; (5) squamous cell carcinoma (SCC). Not only can the cervical exfoliated cells from all the brush with the support of the TCT brush tube, tube of cervical exfoliated cells can also brush, therefore, abnormal cells can be found not only in cervical squamous epithelium, also found abnormal cells in the cervical canal epithelium. Therefore, TCT cervical cytological examination is a more comprehensive and effective screening method of cervical cancer, a large number of data on cervical cancer screening at home and abroad has long been proved this point.
Cervical cancer screening program should be: first cervical cytology, if the result is not unusual, we do not have to do colposcopy and other examinations, of course no longer do cervical biopsy; if the cytologic examination found abnormal cells or suspicious cancer cells, should colposcopy, colposcopy and under direct vision. Take a piece of tissue of the lesion forceps for histopathological diagnosis suspicious. So the cervical cytology screening for cervical cancer is found, the preferred method of early cervical lesions, while TCT and TBS combination of descriptive classification diagnosis is one of the inspection methods and tools at home and abroad the most advanced and scientific.
Screening: who is 18 years of age have had sexual life of women; female sexual life history more than 1 years; early age of first intercourse (< 16) women; fertile women; regular or irregular women taking the pill; abortion women; occasionally abnormal symptoms have been the women did not seek medical treatment; there are more than 2 of female sexual partners; appear abnormal leucorrhea, pruritus vulvae, lower abdominal pain, backache, fatigue, menstruation and other symptoms of women; maintain sexual life especially women around the age of 30; smoking women suspected HPV infection of female. Early signs of cervical cancer: the leucorrhea: early abnormal leucorrhea: no abnormal smell; can be mixed with a bloody, evil smell; irregular vaginal bleeding: in coital bleeding, abdominal bleeding, and bleeding after menopause; cervical erosion: young women with cervical erosion and treatment, or menopause is still have a cervical erosion. All of the above objects are necessary to do cervical cytology TCT.