What is the difference between glomerulonephritis and interstitial nephritis?

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Glomerular nephritis is generally referred to as "nephritis", mainly in glomerular lesions, clinical manifestations of hematuria, proteinuri

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Glomerular nephritis is generally referred to as "nephritis", mainly in glomerular lesions, clinical manifestations of hematuria, proteinuria, edema, hypertension, some patients with renal insufficiency. The renal pathological examination of renal biopsy obtained according to different performance is divided into IgA nephropathy, mesangial proliferative glomerulonephritis, minimal lesions, membranous nephropathy, focal segmental glomerulosclerosis, membranoproliferative glomerulonephritis and other primary glomerulonephritis, including lupus nephritis, kidney damage and some inflammatory rheumatic diseases caused by secondary glomerulonephritis. The treatment is different because of the different clinical pathological manifestations of kidney. Therefore, renal biopsy is often required in patients with glomerulonephritis.

Interstitial nephritis is often caused by infection, urinary tract obstruction and reflux, autoimmune diseases, drugs, metabolic toxins, radiation damage, genetic diseases, and so on. Clinical manifestations of water, electrolyte and acid-base balance disorders and anemia, renal insufficiency, diabetes, amino acid, phosphate, renal tubular proteinuria, etc.. Treatment is mainly to eliminate the predisposing factors, treatment of primary disease and symptomatic treatment. Pyelonephritis (infectious interstitial nephritis) mainly for bacteria (very few viruses, fungi, chlamydia and mycoplasma infection) caused by pelvic mucosa. The clinical signs of waist soreness discomfort, intermittent urination, urination discomfort, accompanied by fever, fatigue, anorexia and renal tubular function injury, disease can lead to sustained development of uremia. Acute infection of systemic infection symptoms, often fever, chills, pain etc.. The long-term use of nephrotoxic drugs (analgesics, heavy metal preparation, Chinese medicine Aristolochia etc.) is also an important reason.

Chinese Medical Association

 

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