1 Helicobacter pylori test:Helicobacter pylori infection is the main cause of chronic gastritis, which should be used as a routine diagnosti
1 Helicobacter pylori test:
Helicobacter pylori infection is the main cause of chronic gastritis, which should be used as a routine diagnostic method. In general, the routine examination of biopsy specimens should be routinely performed for the detection of Helicobacter pylori. The first rapid urease test, and urea reagent containing phenol red in red. In order to determine the relationship between the number of Helicobacter pylori and inflammation, in addition to the routine pathological section, do Giemsa staining or Warthin-Starry staining. If the drug sensitivity test can be used to guide clinical medication, it should be micro aerobic culture. In order to distinguish the type of Helicobacter pylori infection in patients, but also to carry out PCR examination at the level of molecular biology.
Methods for the detection of Helicobacter pylori (HP), as well as 13C or 14C urea breath test, were used to detect antibodies against Helicobacter pylori (HP) in blood or saliva. If the gastric mucosa with Helicobacter pylori infection, oral administration of labeled urea urease will be decomposed into 13Co2 or 14Co2 from lungs. The sensitivity was 96% and the specificity was up to 97%. ELASA method can be used to detect Helicobacter pylori antibody (IgG and IgA) suitable for population screening and screening.
2 serological examination:
Gastrin, vitamin B12, anti parietal cell antibody. Atrophic gastritis can be caused by Helicobacter pylori infection or autoimmune imbalance. So if found in the stomach body gastritis, and suspected atrophic gastritis, should check the above indicators. In chronic gastritis, gastric atrophy, serum gastrin levels were significantly higher in G17, pepsinogen I or pepsinogen I/II ratio decreased; antral atrophy, decreased levels of serum gastrin G17, pepsinogen I or pepsinogen I/II ratio is normal; the reduction of both gastric atrophy. Detection of serum gastrin and pepsinogen G17 I and II are helpful to determine whether the gastric mucosal atrophy and atrophic place.
3 endoscopy and biopsy:
Gastroscopy is the gold standard for diagnosis of chronic gastritis".
L chronic superficial gastritis can be seen punctate or punctate erythema, mucosal roughness, visible bleeding spots or erosion. The mucosa was red and white, mucus secretion, mucosal fragility, plica hyperplasia, mucous surface visible white exudate, biopsy of superficial gastritis change.
L of chronic atrophic gastritis mucosa is more a pale or grey, there are red and white, fold flat thin and flat, transparent purple submucosal vascular texture, reduce mucus or dry lake. The lesions can be diffuse or unevenly distributed. The mucosa can be rough, because some parts of foveolar hyperplasia, can be expressed as granular or nodular. Gastric body parts can also be seen in a few scattered lesions.
L lesions of the gastric body gastritis are more common in the stomach, gastric antrum is normal or scattered in the lesions.
L is very important for the diagnosis of chronic gastritis. Helicobacter pylori infection in gastric mucosa, gland atrophy, intestinal metaplasia, dysplasia, endoscopic cannot accurately judge. Biopsy pathology is required.
L biopsy material is also very important, improper selection will affect the diagnosis results. A biopsy at one site does not represent the entire stomach. The need for clinical, endoscopic examination and careful biopsy, will improve the correct diagnosis rate. Material should be of sufficient size, should include the mucous membrane and mucous membrane muscle layer, the material is too shallow to judge whether there is atrophy, can not rule out the possibility of atrophy.
4 gastric analysis:
Chronic gastritis and gastric lesions are diffuse and severe, there is often a lack of gastric acid, five peptide gastrin test without gastric acid secretion. Chronic gastritis does not affect gastric acid secretion, but sometimes more. If a large number of G cells are destroyed, gastric acid secretion is reduced. At present, most units have not yet carried out this project.
5 gastric motility test:
The condition of the unit can be used to test gastric emptying function. A variety of methods can be used to assess this complex digestive function. Currently, the gold standard for the determination of gastric emptying. Non scintillation scanning methods, such as ultrasound, radioactive and magnetic resonance imaging technology can also be used in clinical, and many of the intubation technology, because of the invasion, the operation is no longer using complex.
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