What are some of the commonly used drugs in the eradication of Hp? What problems should be paid attention to?

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In the "Third National Hp infection," the Mount Lu consensus opinion put forward the Hp eradication treatment of commonly used drugs:A, PPI:

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In the "Third National Hp infection," the Mount Lu consensus opinion put forward the Hp eradication treatment of commonly used drugs:

A, PPI:

There are esomeprazole (E) 20 mg, ray Bella with (R) 10 mg (L) 30 mg, lansoprazole and omeprazole (O), 20 mg pantoprazole (40 mg P).

Two, RBC: of ranitidine bismuth citrate

Three, antibiotics:

A: amoxicillin

C: clarithromycin

M: metronidazole

T: tetracycline

F: furazolidone

L: levofloxacin

B: (bismuth bismuth potassium citrate bismuth pectin etc.)

Matters needing attention:

A,

1 PPI triple therapy (PPI+) of the two antibiotics for 7 days, is still the first choice;

2 when metronidazole resistance rate is below 40%, first consider the PPI+M+C/A;

3 when the rate of clarithromycin resistance is less than or equal to 15%~20%, first consider the PPI+C+A/M;

4 RBC triple therapy (RBC+, two antibiotics), can still be used as first-line treatment program;

5 to improve the eradication rate of Hp, to avoid secondary resistance, the quadruple therapy as first-line therapy;

The 6 Hp of metronidazole and clarithromycin resistance, and furazolidone, tetracycline and quinolones (such as levofloxacin and moxifloxacin) for drug resistance rate is low, the treatment effect is relatively good, can be used as the first choice of treatment;

7 at least 2 weeks prior to the eradication of Hp, Hp may not be used for the inhibition of drugs, such as PPI, H2 receptor blockers, bismuth and antibiotics, so as not to affect the efficacy;

8 medication method: PPI morning and evening meals before taking antibiotics after meals.

Two,

1 treatment principles: quadruple therapy (PPI+ bismuth + two antibiotics) is still the first choice, treatment should be considered again initial treatment conditions, to avoid the repetition of the initial treatment of antibiotics.

2 large doses of metronidazole (0.4 TID) can overcome the resistance to tetracycline resistance rate is low, the price is cheap, and bismuth quadruple therapy and PPI can be used for remedial treatment or treatment again.

3 the drug resistance rate of furazolidone is low, and the effect is good, but we should pay attention to the adverse drug reactions.

4 for metronidazole and clarithromycin resistance, quinolones drugs such as levofloxacin and moxifloxacin as salvage therapy or treatment again, can obtain better curative effect.

This article reprinted from http://user.qzone.qq.com/345040900/blog/1417501849

 

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