Definition of menopause

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Menopause is usually a permanent termination of physiologic menstruation or a permanent loss of the function of the synthetic estrogen in th

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Menopause is usually a permanent termination of physiologic menstruation or a permanent loss of the function of the synthetic estrogen in the treatment of breast cancer. Menopause standards are as follows:

After bilateral ovariectomy;

60 years of age or older;

Age less than 60 years, and in the absence of menopause chemotherapy and tamoxifen, toremifene and ovarian function suppression therapy under the condition of more than 1 years, the serum FSH and estradiol levels in postmenopausal women with range at the same time; while taking tamoxifen, toremifene, age < 60 years postmenopausal patients must be continuous detection of serum FSH and estradiol within the scope of postmenopausal estrogen level.

In addition, also need to pay attention to:

Women who are being treated with LH-RH agonists or antagonists are unable to determine whether or not menopause.

Women had no adjuvant chemotherapy before menopause, menopause, menopause cannot be used as a judgment basis, because patients in chemotherapy may stop ovulation or amenorrhea, but ovarian function may still be normal or may recover.

For chemotherapy-induced menopause women, if consider the use of aromatase inhibitors as endocrine therapy, you need to consider the effective suppression of ovarian (bilateral ovarian resection or inhibition), or continuous monitoring the level of FSH/ or estradiol has been confirmed in patients after the vast state.

 

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