Special considerations for radiotherapy after breast conserving therapy for invasive breast cancerBreast conserving therapy including radiot
Special considerations for radiotherapy after breast conserving therapy for invasive breast cancer
Breast conserving therapy including radiotherapy contraindications:
* radiotherapy during pregnancy
Diffuse calcification of suspicious or malignant appearance
* extensive lesions can not be achieved by a single incision with local resection to achieve a negative cutting edge with satisfactory cosmetic results
* borderline pathology diffuse positive
* previous chest wall or breast radiotherapy; it is necessary to know the dose of the prescription and the target area.
* the activity of connective tissue disease involving the skin (especially scleroderma and SLE)
* tumor > 5cm (grade 2B)
* pathological positive margin
A woman with a known or suspected predisposition to breast cancer:
In breast conserving therapy may have ipsilateral breast recurrence or increased risk of contralateral breast cancer
In order to reduce the risk, can consider bilateral prophylactic mastectomy
(see genetic / familial risk assessment for breast and ovarian NCCN guidelines).
NCCN guide first edition 2016