Considerations for the use of

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You use lapatinib with friends, I do the following brief disambiguation methods of lapatinib use and precautions:1, lapatinib:At present, la

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You use lapatinib with friends, I do the following brief disambiguation methods of lapatinib use and precautions:

1, lapatinib:

At present, lapatinib is 1250mg each time, 1 times a day, fasting oral use. If combined with the food will increase the drug concentration, increased toxicity. Estimation of small dose of lapatinib with food and clothing can obtain larger dose of lapatinib were the same therapeutic effect. But because the diet drug absorption interference, blood concentration may be affected by the impact of food fluctuations, clinical research and therefore are not recommended in the instructions for use, very difficult economic patients, not in the medication under the guidance of a doctor to model.

Because each patient showed a different response, may be appropriate to reduce the amount of.

For the use of advanced expression of lapatinib resistant HER2 breast cancer patients.

2, the adverse reaction, for it:

Diarrhea, mild diarrhea by Smecta diarrhea, diarrhea, can consider to stop drug use, some patients with diarrhea to stop severe diarrhea, please return to the hospital to visit.

Mild rash, rash can use antihistamines such as chlorpheniramine, Calamine Lotion, please return to the hospital to severe rash.

If the cardiac toxicity, chest tightness, heart palpitations, shortness of breath and discomfort after the event, please review the ECG and echocardiography, cardiac toxicity usually caused by lapatinib is reversible.

Other rare adverse reactions do not detail.

 

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