Hepatitis C transmission pathway1 blood transmission: HCV is the main route of transmission, mainly:(1) transmission by blood transfusion an
Hepatitis C transmission pathway
1 blood transmission: HCV is the main route of transmission, mainly:
(1) transmission by blood transfusion and blood products. Since the screening of anti -HCV in blood donors in China in 1993, this approach has been effectively controlled. But because of the quality of anti -HCV and anti -HCV window detection reagent is not stable and the small number of infected persons do not produce anti -HCV, therefore, can not be completely sieve except HCV RNA positive, a large number of blood transfusion and dialysis may still be infected with HCV.
(2) dissemination of damaged skin and mucous membranes. This is the most important mode of transmission, in some areas, due to intravenous drug HCV transmission accounted for 60% ~ 90%. The use of non disposable syringes and needles, without strict disinfection of dental instruments, endoscopy, invasive procedures and acupuncture is also an important way of transcutaneous transmission. Some traditional methods may lead to skin damage and blood exposure was also associated with the spread of HCV; sharing razors, toothbrushes, tattoos and pierced earrings hole is HCV potential blood transmission mode.
2 sexual transmission: the risk of HCV infection is higher in patients with HCV infection and sexual abuse. At the same time with other sexually transmitted diseases, especially those infected with human immunodeficiency virus (HIV), the higher the risk of infection with HCV.
3 mother to child transmission: Anti -HCV positive mothers HCV transmission to risk newborn is 2%, if the mother in childbirth HCV RNA positive, the risk of spreading can be as high as 4% ~ 7%; with HIV infection, the risk of transmission increased to 20%. High viral load of HCV may increase the risk of transmission.
part of the transmission of HCV infection is unknown. Kissing, hugging, sneezing, coughing, food, drinking water, and common tableware cups, without skin damage and other blood exposed contact is generally not spread HCV.