Does a slight rise in total bile acid indicate a serious liver injury?

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Patient: description of the disease (the main symptoms, when the disease was discovered in October 2007 two semi hepatitis B HBeAg, liver fu

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Patient: description of the disease (the main symptoms, when the disease was discovered in October 2007 two semi hepatitis B HBeAg, liver function; ALT3178, AST2132, TBLL130.2 after 20 days of hospitalization in patients with liver function; ALT90, AST66, TBLL29.7, DB10.6A/G1.07, hospital. At home by the doctor, one month of treatment, combined with western medicine on two; small sanyang. HBVDNA3.25*4. liver function A/g49.6/19.4. Continued treatment until February 27, liver function was normal, DNA negative, and HBS, HBE, HBc three positive were detected in half of the two. The doctor suggested drug withdrawal for 3 months, during which every month I have to do a check, is a normal liver function, negative DNA {500} is less than HBS, HBE, HBc three positive. At the beginning of the August examination; liver function is normal, DNA negative, two pairs of HBS negative, HBE positive HBC two. Continue to take some Chinese medicine, but also continue to check the end of the year are the same results, that is, no HBS positive. In March this year again, liver function is normal, DNA negative, but the emergence of the HBSag [0.216] and HBE, HBC was positive in three, doctors recommend do not need medication treatment, after repeated examination, liver function is normal, DNA is negative, but in two on HBE, HBC and HBSag were two and HBE, three world HBC wave, a recent inspection in July 18, the results; liver function is normal, HBVDNA negative, HBE positive, HBC two. Today, we did a check; two of them were anti HBC positive, liver function, other normal, total bile acid 33.1.HBVDNA negative. Is the high total bile acid in this condition a sign of severe liver injury? I am this kind of circumstance can you hit second liver vaccine? What do you need to do?

Peng Jie Department of infection of Nanfang Hospital of Southern Medical University:

1, high total bile acid is not a serious liver injury.

2, you do not need to fight hepatitis B vaccine.

3, regular review of liver function, HBVDNA, AFP, B ultrasound.

Patient: Thank you. I also want to ask a doctor Peng, I saw a total bile acid high argument on the Internet, said: when transaminase, bilirubin and alkaline phosphatase and other indicators to normal, serum total bile acid level is still high, this may be due to liver cell function for disorders, such as the reasons for the reduction of parenchyma cell. I was worried about my situation is not the case, after all, I have had hepatitis. In addition, like me, the total bile acid 33, is not it can be said to be higher? I have a slight problem with cholecystitis.

Peng Jie Department of Nanfang Hospital of Southern Medical University infection: please be assured that it does not matter. It is not possible for every person to be able to detect each index in clinical biochemistry. Some indicators, such as total bile acid, are slightly less than normal. Don't get into a dead end, especially non medical professionals.

 

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