C two times according to the "guide" treatment, why long response is not good?

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In patients with hepatitis C: two according to the "guide" treatment, long-term response is not good. 1 March 2007 80, examination of alanin

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In patients with hepatitis C: two according to the "guide" treatment, long-term response is not good. 1 March 2007 80, examination of alanine, aspartate 75, further examination 6 RNA 10. Then the antiviral (interferon plus ribavirin treatment Sinogen). The treatment response rapidly, liver function, RNA were normal. Continuous treatment for 24 weeks. October 27, 2007 71: review of liver function alanine, aspartate 52. RNA was quantified as 10 of the 5 party. 2, October 2007 to January 2009, continuing antiviral therapy of continuous medication for 14 months (5 months in Anfu dragon 500 thousand units + Leigh Bhave Lin; 4 months, Enan 600 thousand units + Leigh Bhave Lin; 6 months hapgen 500 thousand units + Leigh Bhave Lin) were more than three times a week. During the inspection are normal. Drug withdrawal for 3 months, namely April 25, 2009 Review of the results: 216 alanine, aspartate 103, HCV-RNA is 6 times 10. Such as continuing treatment, where can do HCV-RAN typing test? Need puncture? How much does it cost?

Peng Jie Department of Nanfang Hospital of Southern Medical University from infection: the information you provide you with visible, treatment is not standardized, it may be an important cause of treatment failure. Obviously, the interferon dose (50--60 million units) is too small, such as the use of short acting interferon, usually with 300--500 million units; in addition, if conditions permit, the last use of international standards: interferon + Leigh Bhave Lin. According to the Chinese people infected with hepatitis C virus, the vast majority of gene type 1, therefore, genotyping is not important, according to a year of treatment can be. Half a year of treatment is not enough, so the first time after the withdrawal of the drug quickly relapse. Of course, it is best to have a liver puncture before antiviral therapy, so as to understand the degree of liver pathological changes and evaluate the therapeutic effect. The cost of liver puncture is not high, our hospital charges about 700 yuan. Welcome to our hospital visits, I see "personal time.

 

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