The long-term antiviral therapy for many years, is still a big world, how to do?

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Question: in patients with hepatitis B HBeAg, abnormal liver function before the treatment, but less than two times by entecavir therapy, im

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Question: in patients with hepatitis B HBeAg, abnormal liver function before the treatment, but less than two times by entecavir therapy, immune therapy the liver function is normal, not detected by DNA, to go to the clinic recently, the doctor gave me two suggestions: 1, withdrawal, such as abnormal liver function, more than two times continue to antiviral therapy. 2, continue to use, but I like the e antigen titer is so high to small three do not know how many years. So confused?

Nanjing Gulou Hospital infection Wu Chao replies: thanks for your trust, provide you with the following suggestions: 1) please consider to continue to adhere to the antiviral treatment, because despite the slow progress, but in any case the liver function is normal, the disappearance of DNA is a very good condition, withdrawal is the wrong choice, and may cause serious consequences. 2) consider the liver function before the treatment is not high, not more than two times higher than normal, and grace for Cave (if it is made worse) on the part of the long-term treatment of late effect will be weakened, the replacement for the advice for Nuo Fuwei (trade name Wei Reed, the hospital should have one capsule daily, 490 yuan a month). (3) regular testing of two semi quantitative, if the E antigen and S antigen continued to decline, then effective. It can also be used as a combination of long-acting interferon when the surface antigen is less than 1000 E antigen is less than 100. 4) to emphasize that the efficacy of antiviral drugs are all inhibit the virus, and no clear ability, ability of clearing the virus's own immune function determines, therefore, need to have good habits, healthy lifestyle, exercise, strong physique, clear the virus to use faster. Due to the fact that hepatitis B can eventually be cured, so, need to have confidence, but also to have the patience, many people after 8 or even 10 years to achieve a clinical cure. Above for reference. Recommendation: click here to refer to the article "chronic hepatitis B can be cured? "

 

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