Factors affecting the efficacy of liver cancer

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Factors affecting the efficacy of liver cancerAt present, the clinical treatment of liver cancer is more and more complicated, and there are

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Factors affecting the efficacy of liver cancer

At present, the clinical treatment of liver cancer is more and more complicated, and there are some preferences in the treatment of traditional Chinese medicine. Some patients with liver cancer treatment effect is good, some patients with liver cancer treatment results are not satisfactory. We believe that the following factors affect the clinical efficacy of liver cancer.

1, the concept of liver cancer treatment. Liver cancer is both local and systemic. Therefore, the current emphasis on the treatment of liver cancer should be integrated, multidisciplinary, multi method combination of good results. The effect of a single treatment is poor. The diagnosis and treatment of liver cancer should be closely related to the Department of hepatobiliary surgery, the Department of internal medicine, the Department of internal medicine, the Department of interventional radiology and the Department of imaging diagnosis. Many methods including surgical resection (including liver transplantation), radiofrequency ablation (RFA), cryoablation, percutaneous transcatheter hepatic arterial chemoembolization (TACE) and radiotherapy (including image positioning of radioactive seeds implantation) and chemotherapy. Comprehensive treatment includes two kinds: one is the different method to eliminate the tumor (resection, local ablation, TACE, etc.) the comprehensive and sequential application, with TACE reduced after the resection of large hepatocellular carcinoma, called "liver descending period after cutting", is a typical example of comprehensive and sequential application; two the elimination of liver cancer and tumor and immune regulating the synthesis and application of sequential. If the tumor immune enhancer + methods, eliminate tumor + antiviral (hepatitis B or C virus) treatment, tumor removal + anticancer drugs (including Chinese Medicine).

2, early diagnosis and early treatment. Since 70s, our country has carried out the resection of liver cancer in the last century, more than 30 years of clinical experience has shown that small hepatocellular carcinoma (diameter less than 3cm or less) after resection of liver cancer clinical effect is good. In fact, for the treatment of any cancer, the International Alliance for cancer prevention is still the slogan of "early detection can save lives". Liver cancer is even more so. Our country is 90% in patients with hepatocellular carcinoma and liver cirrhosis on the basis, therefore, age more than 40 hepatitis B patients, should regularly check blood ultrasound, CT, AFP. It is found that the majority of patients have good prognosis and long-term survival after liver resection or liver transplantation or local ablation.

3, liver cancer resection experience and technology. Surgical resection of liver cancer is still the most basic and effective method for the treatment of liver cancer. Complete resection of liver cancer lesions, the treatment effect is good, patients and their families are also more assured. But the same is the removal of liver cancer, some patients relapse after surgery, some patients better results. This is related to the surgical technique and experience of the surgeon. Our experience shows that intraoperative blood loss and postoperative complications, liver function, recovery time and long-term survival rates have a certain relationship; surgery for liver cancer move, extrusion, can cause cancer cell hematogenous metastasis, etc.. Therefore, the current emphasis on precise hepatectomy, the comprehensive application of hepatic vascular occlusion, intraoperative ultrasound, portal vein staining, the anatomy of the liver lobe hepatic vein as the center, complete excision of the lesion and maximize the retention of the remnant liver blood supply and blood outflow tract, biliary tract. Our department in recent years to carry out a wide range of liver cancer "fence" surgery, can reduce bleeding during operation, and can effectively avoid the spread of blood hepatocellular carcinoma cells induced by tumor, move the extrusion operation, achieved good clinical effect.

4, individualized treatment. For patients with liver cancer, the appropriate treatment should be selected according to the patient's liver cancer, liver function, general condition and economic situation. Small hepatocellular carcinoma (HCC) can be treated by surgery or liver transplantation, and it is feasible to intervene or minimally invasive ablation of unresectable liver cancer, and Sorafenib (Sola Fini), etc.. Without considering the specific circumstances of the patient, not the syndrome differentiation, often take home the counter, not only failed to cure patients or his life, but shortened the survival time of patients.

5, actively prevent recurrence of liver cancer. Liver cancer recurrence after surgical resection, which is one of the most important causes of liver cancer. The blood supply of the liver and liver cancer is rich, easy invasion of portal vein, hepatic vein, or intraoperative imaging can find small lesions and in the majority of patients with hepatocellular carcinoma complicated with liver cirrhosis, liver resection or other methods for the treatment of liver cancer, its many cirrhosis nodules also easily become the new liver cancer. Therefore, patients with liver cancer after surgery should be regularly reviewed, early detection of recurrent liver cancer, positive treatment, can still achieve good results. The use of anticancer drugs, the use of immunosuppressive agents and antiviral drugs, can reduce the recurrence rate after resection or ablation of liver cancer.

 

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