Hepatocellular carcinoma (HCC) is a common malignant tumor. According to the pathological types, they were divided into hepatocellular carci
Hepatocellular carcinoma (HCC) is a common malignant tumor. According to the pathological types, they were divided into hepatocellular carcinoma, cholangiocarcinoma and mixed cell carcinoma. In our country, the high incidence of liver cancer area including Jiangsu Qidong and Guangxi Fusui Haimen County, Guangdong, Shunde and other places. At present, it is considered that the occurrence of liver cancer is the result of multiple stages and multiple factors, such as the process of initiation, promotion and progression of cancer, and the mutation of multiple genes. So who are more likely to suffer from liver cancer in the end, the need to pay more attention to it? According to the available data, hepatitis virus, aflatoxin and drinking water pollution are the three major factors of liver cancer.
It is often seen that the patients with liver cancer experience the course of acute hepatitis, chronic hepatitis, cirrhosis and liver cancer. The relationship between viral hepatitis and liver cancer is hepatitis B and C HBV and HCV infection. Often HBV high prevalence area is also a high incidence of liver cancer, and HCV infection is one of the main causes of liver cancer in developed countries. Therefore, for patients with chronic hepatitis B or hepatitis B carriers, the need to be highly alert to the possibility of carcinogenesis. More importantly, women with chronic hepatitis B should be closely monitored during the entire pregnancy, to avoid the occurrence of neonatal hepatitis B virus infection, reduce the risk of liver cancer.
Aflatoxin is another important factor in carcinogenesis, metabolites of aflatoxin for aflatoxin B1, has a strong carcinogenic effects, in moldy corn, peanuts and other foods, food is in serious pollution of the yellow aspergillus toxin B1, the incidence rate is higher. Suitable for high temperature, high humidity in the growth and reproduction of the environment, long-term consumption of food containing this toxin can induce liver cancer. At present, the minimum dose of liver cancer is only 10 micrograms per day. At the same time, aflatoxin has a synergistic effect with HBV infection.
The occurrence of tumor is always the result of the interaction between heredity and environment. The occurrence of liver cancer has familial aggregation, suggesting a certain relationship with heredity. At the same time an important factor in common life environment is the aggregation of high, epidemiological survey shows that the high incidence area of hepatocellular carcinoma and liver cancer related to drinking water sources, water pollution is one of the independent risk factors of liver cancer incidence and high mortality of liver cancer in the drinking pond ditch water, river water and well water drinking and the incidence is low. In addition, the soil and crops in the lack of certain trace elements such as selenium, molybdenum and other related. In addition, alcoholic liver fluke infection, smoking, exposure to pesticides and has some relationship with the occurrence of liver cancer. In recent years, a large number of epidemiological studies show that metabolic syndrome is closely related with the occurrence of primary liver cancer, a common manifestation of the metabolic syndrome as central obesity, dyslipidemia, hypertension and impaired fasting glucose in the liver, the performance is usually non alcoholic fatty liver disease.
For the population of HCC are favored, to actively carry out the "water, mildew, anti hepatitis", namely in the high incidence of liver cancer will be changed into deep water county pond water, to eat rice instead of corn, the popularity of hepatitis B vaccination. At the same time to promote a healthy lifestyle, quit smoking and alcohol, appropriate to add trace elements, to avoid contact with possible carcinogens, etc..