Advantages and disadvantages of hormone therapy in perimenopausal period

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After entering the age of 45 years, women have been close to or into the perimenopausal period, and even some women have menopause. Menopaus


After entering the age of 45 years, women have been close to or into the perimenopausal period, and even some women have menopause. Menopause is an inevitable physiological process of women, but after menopause, the body will appear a series of symptoms, including sweating, hot flashes, unstable mood, sleep disorders, low libido, sexual disorder affects the quality of work and life. In addition to urogenital organs atrophy, prone to vaginitis, urethritis and other inflammatory diseases, frequent urination, urinary incontinence, uterine prolapse and other organic diseases after menopause, the old man entered the state.

Why do women have a significant period of menopause? This has something to do with our ovaries. The ovary is an important reproductive organ of the female, at the same time, it is also an endocrine organ, which is responsible for the secretion of female hormones. But it and other endocrine glands are not the same place: endocrine gland function of the other end with the end of life (with the exception of some endocrine diseases), these organs once abnormal, must be treated, otherwise it will seriously affect people's lives and health, but the ovaries in postmenopausal women have no function, no matter the whole life how long, it could no longer work, everyone is so, is a normal phenomenon, not sick, can not treated. When the ovaries began to work, the decline in estrogen levels in the process of a series of symptoms. The symptoms disappear when estrogen goes down to menopause and stays low.

Due to the improvement of living standards and medical standards, people's lives longer than in the past a lot, 70 year old is not very old, live to the age of 80 years old, is not a strange thing to do at the age of 90. We not only want to live long, want to live better, wish you forever young, so from the last century began in 50s and 60s to start hormone replacement therapy, estrogen replacement therapy in perimenopausal and postmenopausal.

After half a century of hormone therapy, has been sought after, but also experienced many disputes, but also caused panic. The terms are also changed: estrogen replacement therapy, hormone replacement therapy, hormone therapy. At the beginning, it is believed that all the symptoms of menopause are due to estrogen deficiency, so it is only a simple supplement of estrogen, so called estrogen replacement therapy. Later found the simple application of estrogen has many complications: may cause endometrial disease, estrogen plus progestin therapy was given, so called hormone replacement therapy. Later, the use of hormones is not only used in postmenopausal. When entering menopause symptoms appear, it can be treated, hormone therapy not only apply to the hormone to supplement or substitute a very low level after the onset of symptoms, when pre menopausal hormone therapy or collectively hormone therapy menstrual disorders.

So what are the advantages and disadvantages of hormone therapy?

Advantage is:

1 ease due to estrogen deficiency induced by hot flushes, sweating, irritability, depression, fatigue, sleep disorders, heart palpitations, headache and other symptoms of menopause;

2 treatment of senile urogenital atrophy;

3 prevention and treatment of postmenopausal osteoporosis; osteoporotic fractures occurred within 1 years, died of complications of up to 20%. About 20% of patients with fracture can die from pulmonary embolism and pneumonia within 1 years.

4 reduce the incidence of coronary heart disease;

5 prevention of Alzheimer's disease;

6 reduce the incidence of colon cancer;

7 to improve the elderly women ataxia.

Disadvantages: possible side effects:

1 endometrial problems: estrogen can promote endometrial cell mitosis, promote endometrial hyperplasia. Progesterone can inhibit endometrial hyperplasia. However, due to the low degree of malignancy, good tissue differentiation and early detection of endometrial cancer, estrogen therapy does not increase the mortality of endometrial cancer. In the application of hormone treatment, the endometrial thickness should be monitored regularly, for patients with irregular uterine bleeding or B ultrasound showed endometrial thickness of 5mm or more, endometrial biopsy should be performed. In

The 2 part: Women's breast problems in the use of HRT occurs when the breast pain and estrogen and progesterone are related. The relationship between hormone therapy and breast cancer is still controversial, and it is generally believed that the use of hormone replacement for more than 5 years, may increase the risk of breast cancer. Therefore, regular examination of the breast is essential, early detection and early treatment can reduce the mortality of breast cancer. In

3 oral estrogen reduced acid secretion, increased cholesterol saturation of bile, so as to increase the incidence of gallstones in patients with cholelithiasis, should be used with caution in oral estrogen or to transdermal estrogen. The

4 estrogen especially synthetic estrogen can increase blood clotting function caused by thrombophlebitis, so thrombophlebitis patients should not use estrogen. The advantages and disadvantages of hormone replacement therapy in perimenopausal period are objective, but the International Menopause group experts believe that the advantages outweigh the disadvantages. The doctor will according to different conditions of patients, whether there are indications and contraindications to inform whether patients need replacement therapy.

Menopausal women and do not blindly follow the trend of hormone replacement therapy, do not be afraid of hormone therapy. Under the guidance of doctors, and regular physical examination, the necessary hormone treatment will significantly improve the quality of life.

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