How to treat bone metastasis of colorectal cancer?

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What are the risk factors for colorectal cancer?According to the results of our study, rectal cancer with lymph node metastasis ([1]) is mor

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What are the risk factors for colorectal cancer?

According to the results of our study, rectal cancer with lymph node metastasis ([1]) is more likely to occur than other colorectal cancers.

Which parts are prone to bone metastases?

According to the results of our study [1], spine and pelvis are more prone to bone metastases.

How to diagnose bone metastasis of colorectal cancer?

Bone scan, CT, MRI and PET-CT can be used for diagnosis.

The main objectives of comprehensive treatment of colorectal cancer bone metastases are: (1) to relieve pain, restore function, improve quality of life. (2) to prevent or delay the occurrence of bone related events (pathological fractures, etc.). (3) to control tumor progression and prolong survival.

Including the treatment options for colorectal cancer bone metastasis: (1) pain medication; (2) bisphosphonate therapy; radiotherapy; (3) (4) (5) surgical treatment; symptomatic support and rehabilitation; (6) chemotherapy, molecular targeted therapy of anti tumor therapy.

Surgical treatment of colorectal cancer with bone metastases? 1) the patient is expected to survive for more than three months. 2, the whole body condition is good, can tolerate the operation wound and anesthesia. 3. It is expected that the quality of life of patients after surgical treatment is better than that before surgery, and it can be operated immediately. 4) the primary tumor is expected to have a longer disease-free period after treatment. 5. After systemic treatment, osteolytic lesions tended to be limited and bone mineral density increased. 6) solitary bone metastasis. 7) high risk of pathological fracture.

[1] Sun C, Deng Y, Zhou HY, Hu ZQ. factors the development metachronousbonemetastasisin colorectal patients after curative resection. Int J Surg.2015 Sep (cancer of); 21:145-9. (Risk)

 

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