Genital herpes (GH) is a sexually transmitted disease caused by herpes simplex virus (HSV) infection in the genital and anal mucosa. Herpes
Genital herpes (GH) is a sexually transmitted disease caused by herpes simplex virus (HSV) infection in the genital and anal mucosa. Herpes simplex virus (HSV) 1 (HSV_1) and herpes simplex virus type (HSV-2) cause genital herpes. Most genital herpes is caused by HSV-2. The disease occurs mostly in sexually active young people, mostly 20-30 years old. Infected persons may or may not have unsafe sexual behavior, multiple sexual partners, or a history of sexual partners.
The source of infection is genital herpes patients and asymptomatic with virus.
There are three routes of transmission: 1 mainly through sexual contact, anal sex can occur in the anus and rectum damage;
2 mother to child transmission, women with genital herpes, the fetus can be infected in utero, but also due to premature rupture of amniotic membrane and retrograde infection, or in the process of infection;
3 indirect contact, a small number of people can be infected by close contact with daily necessities.
The incidence of the disease is increasing rapidly, and it is prone to relapse, which is more and more concerned due to the serious infection of the newborn and fetus.
Pathogenesis: contact with infected persons, genital skin and mucous membrane by friction, herpes simplex virus through small cracks into the skin mucous membrane keratinocytes. Virus replication in the cell, and directly spread to the surrounding cells, so that infected epidermal cells, causing skin damage. Some of the virus is cleared by the immune response of infected people, but some of the viruses evade the defensive response of the infected person and remain in the ganglion for a long time. Infected by bacterial infection, trauma, menstrual cramps, trauma and low immunity under such circumstances, the virus can recovery and RE activated by the ganglion of the affected area often return to the skin and mucosa and recurrent infections.