Complication of diabetes mellitus. Mainly due to diabetes intake of carbohydrates (sugar) can not be converted into energy and sugar in the
Complication of diabetes mellitus. Mainly due to diabetes intake of carbohydrates (sugar) can not be converted into energy and sugar in the form of blood volume, or the conversion of heat energy can not be satisfy the needs of human life activities, caused by hyperglycemia, water, electrolyte, and protein, fat and a series of metabolic disorders caused by, and is the main reason death or disability. Which:
Macrovascular complications are often caused by excessive intake of fat, or too much fat is used to replace carbohydrates (sugars), resulting in insufficient heat energy. The mechanism of lipid metabolism disorder or excessive lipid metabolism in the blood vessels, which increases the chance of deposition or attachment in the vascular wall. Predilection sites for the heart, brain, limbs and other large vessels. For example: compared with patients without diabetes earlier onset of angina pectoris (long duration, lesser degree of pain, Dilational medicine invalid) and myocardial infarction (as painless), refractory heart failure, cerebral infarction, gangrene and other vascular diseases. According to statistics, there are about 50 of the number of patients who have been accompanied by lipid metabolism disorder - - - 80%. Hypertension is about 30 - 40%;
Small vascular complications are often caused by poor blood glucose control. At the core of the mechanism is the high blood glucose or blood glucose toxicity, resulting in small vascular tissue degeneration (endothelial cell like change or chromosome abnormalities). The predilection site is rich in blood vessels, such as fundus, kidney and so on. For example: eye fundus retinopathy, or the retinal microaneurysm, hemorrhage, exudation, neovascularization, machine of hyperplasia, retinal detachment and vitreous body hemorrhage, and conjunctival vascular changes, iris, iris rose rash, regulating muscle paralysis, low intraocular pressure, glaucoma, cataract, bleeding through refraction abnormal, optic neuropathy, extraocular muscle paralysis. According to statistics, the number of patients with diabetic retinopathy has been accounted for about 20 of the number of patients - - - 30%. Although the majority of patients with slow progress, but the rapid development of a small number of patients, can be blind in the short term. Renal lesions can occur intermittent or persistent proteinuria, hypoproteinemia, anemia, edema, etc., and in the current conditions, most difficult to reverse. Severe renal failure, life-threatening. According to statistics, there are about 10 of the number of patients who have been accompanied by microalbuminuria, - - 20%;
Nerve cells for complications caused by poor glycemic control, clinical common peripheral neuropathy caused by abnormal sensation, pain, movement disorders, stomach, intestine, bladder and vasomotor dysfunction, spinal cord lesions caused by spinal muscular atrophy, pseudotabes, amyotrophic lateral sclerosis syndrome, lateral sclerosis syndrome myelomalacia, etc.. Nerve electrophysiological studies, the complication rate was above 60%; diabetes decreased immunity and tissue repair ability, often because of carbohydrates (sugar) of heat generated, leading to protein has been widely used for heating or as alternative energy consumption, but also can not timely supplement form. The core mechanism for the formation of human tissues and immune substances, such as: antibodies, complement, etc., lack of raw materials. Clinical manifestations of repeated colds, infections, tuberculosis, wounds, anemia, tumors, etc..
It should be pointed out that timely and effective clinical treatment can prevent or delay the occurrence and development of these complications. However, because it is not always due to increased blood sugar, so even if the blood glucose control is satisfactory, the complications may still occur rapidly and continue to develop.